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Genome-wide maps of histone modification and chromatin remodeler binding in acute myeloid leukemia blast cells and normal hematopoietic cells

ABSTRACT: Genome-wide maps of histone modification and chromatin remodeler binding in acute myeloid leukemia blast cells and normal hematopoietic cells

PROVIDER: PRJNA429274 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6455130_1.fastq.gz	Fastqsanger.gz
	SRR6455130_2.fastq.gz	Fastqsanger.gz
	SRR6455140_1.fastq.gz	Fastqsanger.gz
	SRR6455140_2.fastq.gz	Fastqsanger.gz
	SRR6455131_1.fastq.gz	Fastqsanger.gz

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Genome-wide maps of histone modification and chromatin remodeler binding in acute myeloid leukemia blast cells and normal hematopoietic cells

Project description:We have used chromatin immunoprecipitation followed by high throughput sequencing to map regions of chromatin remodeler binding accompanied by histone modification state. We have used this data to distinguish between the transcriptional state of regulatory genes in leukemic and normal hematopoietic cells, and thus understand contribution of the chromatin remodeler towards leukemogenesis.

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