Transcriptomics

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Single-cell RNA-seq of ASPM mutant ferret embryonic forebrain


ABSTRACT: As described in our paper "Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size" (Johnson et al., Nature 2018), we used the standard Drop-seq method and analysis of Macosko et al. (2015) to capture, sequence, and analyze mRNA from single cells from Aspm wild-type, heterozygous, and knock-out littermate ferrets at embryonic day 35. Bulk reference samples were processed using standard Illumina mRNA-seq library prep and sequencing protocols, and the samples were described previously (Johnson, Wang et al., Nature Neurosci 2015)

ORGANISM(S): Mustela putorius furo

PROVIDER: GSE110010 | GEO | 2018/04/18

REPOSITORIES: GEO

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