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Plasma fatty acid levels and gene expression related to lipid metabolism in peripheral blood mononuclear cells

ABSTRACT: Solid evidence indicates that intake of marine n-3 fatty acids lower serum triglycerides, and that replacing saturated fatty acids (SFA) with polyunsaturated fatty acids (PUFA) reduces plasma total cholesterol and LDL-cholesterol. The molecular mechanisms underlying these health beneficial effects are however not completely elucidated. The aim of this study was to investigate the expression of genes related to lipid metabolism in peripheral blood mononuclear cells (PBMC) depending on the plasma levels of n-6 and n-3 fatty acids and the SFA to PUFA ratio.

ORGANISM(S): Homo sapiens

PROVIDER: GSE111567 | GEO | 2019/03/08

REPOSITORIES: GEO

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