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15 weeks of HFD

ABSTRACT: Heart from dog at 15 weeks of HFD Keywords: repeat sample

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE1116 | GEO | 2004/03/30

SECONDARY ACCESSION(S): PRJNA87227

REPOSITORIES: GEO

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Project description:In order to establish an obese mouse model, female mice were continuously fed with a high-fat diet (HFD) or a normal diet (control) for 16 weeks beginning at three weeks of age. In this paper, these mice are termed ‘HFD mice’ and ‘control mice’, respectively. Accordingly, we call their oocytes ‘HFD oocytes’ and ‘control oocytes’. Substantial evidence indicates that the effects of maternal obesity on embryo/offspring development can be attributed to factors within the oocyte (9). To identify such potential effectors, we performed a comparative proteomic analysis of ovulated MII oocytes from control and HFD mice.

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