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Identification of the gene profiling of Wt1GFP expressing cardiomyocytes at different stages of embryonic heart development [M]

ABSTRACT: Detailed FACS analyses of enzymatically disaggregated embryonic hearts from Wt1GFPKI mice revealed two distinct types of Wt1-GFP-positive cells based on their GFP expression levels: a Wt1-GFP bright population (H) and a Wt1-GFP dim (M) population. Interestingly, when viewed under the microscope, cultured Wt1GFP+ (M) cells were shown to exhibit synchronous contractions that suggest a cardiomyocyte identity. These observations also imply that a population of low Wt1-expressing cardiomyocytes contributes to the formation of the myocardium.

ORGANISM(S): Mus musculus

PROVIDER: GSE113274 | GEO | 2019/09/30

REPOSITORIES: GEO

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