Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from human HCC tissues

ABSTRACT: The expression profiles of twenty paired human liver cancer and adjacent non-tumor tissues We used microarrays to detail the changes of gene expression in human HCC and identified distinct classes of up-regulated and down-regulated genes during this process.

ORGANISM(S): Homo sapiens

PROVIDER: GSE113996 | GEO | 2021/05/03

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression data from paired human primary HCC tissues and adjacent non-cancerous liver tissues.

Project description:Hepatic cirrhosis or advanced fibrosis caused by chronic hepatitis may be the main risk factor contributing to the occurrence of HCC. Growing clinical evidence show that patients with hepatic cirrhosis or advanced fibrosis may have a 7-fold higher incidence rate of HCC than those without, suggesting a crucial role of inflammation-carcinogenesis malignant transformation in HCC development and progression. We used microarrays to detail the global programme of gene expression underlying inflammation-carcinogenesis malignant transformation in HCC and identified distinct classes of up-regulated and down-regulated genes during this process

2021-02-12 | GSE166163 | GEO

Gene expression profiles from the hepatocellular carcinoma (HCC) tissues

Project description:To explore the molecular functions targeted by these miRNAs, we classified genes differentially expressed in clinical HCC samples into six functional clusters based on their functional similarity. 3-paired HCC tissue samples and adjacent normal liver tissues were obtained from patients undergoing surgery and were frozen immediately after surgical resection.

2012-08-31 | E-GEOD-33006 | biostudies-arrayexpress

Expression data from paired human primary HCC tissues and adjacent non-cancerous liver tissues.

Project description:Expression data from paired human primary HCC tissues and adjacent non-cancerous liver tissues.

| PRJNA699510 | ENA

Expression data from ChREBP overexpressing HCC tumors compared to non-tumoral adjacent liver tissue

Project description:ChREBP was stably overexpressed in the liver of C57BL/6J mice through the use of the sleeping beauty transposon system. ChREBP overexpression resulted in HCC tumor development in 12 months. We used microarray analysis to detail the global program of gene expression in ChREBP overexpressing tumors compared to non-tumoral adjacent tissue or compared with normal liver samples from C57BL/6J mice. WE then identified distinct classes of up and down regulated genes.

2022-04-15 | GSE159518 | GEO

Applied Biosystems Human TaqMan Low Density Array (TLDA) in HCC tumor and adjacent non-tumor tissues

Project description:MicroRNAs (miRNAs) are aberrant expressed in hepatocellular carcinoma (HCC) tissue and play a central role in diverse biological processes. We conducted a genome-wide miRNAs screening in 10 pairs of HCC tumor and adjacent non-tumor tissues to test the hypothesis that dysregulation of miRNAs in HCC tumor tissue are partially due to aberrant methylation in relevant miRNAs host genes. Taqman low density arrays were used to examine miRNA profiles in paired HCC tissues, and quantitative RT-PCR was used to validate candidate miRNAs for both discovery and validation sets. A cross-sectional study was conducted in 10 HCC tumor tissues and 10 adjacent non-tumor tissues in Columbia University Medical Center (CUMC), which is approved by the Institutional Review Board.

2014-02-08 | E-GEOD-54751 | biostudies-arrayexpress

circRNA sequencing data of tumors and paired adjacent tissues from HCC patients

Project description:circRNA sequencing data of tumors and paired adjacent tissues from HCC patients

| PRJNA716178 | ENA

Transcriptome sequencing data of tumors and paired adjacent tissues from HCC patients

Project description:Transcriptome sequencing data of tumors and paired adjacent tissues from HCC patients

| PRJNA716181 | ENA

Applied Biosystems Human TaqMan Low Density Array (TLDA) in HCC tumor and adjacent non-tumor tissues

2014-02-08 | GSE54751 | GEO

RNA-Seq data of tumors and paired adjacent tissues from 15 HCC patients

Project description:RNA-Seq data of tumors and paired adjacent tissues from 15 HCC patients

| PRJNA559494 | ENA