Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Analysis of gene expression change between Ishikawa-02 SC and Ishikawa-02 shSOX2

ABSTRACT: We collected total RNA from both Ishikawa-02 SC and Ishikawa-02 shSOX2 and examined mRNA expression profile, comprehensively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE114582 | GEO | 2018/05/18

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Analysis of gene expression change between Ishikawa-02 SC and Ishikawa-02 shSOX2

Project description:Analysis of gene expression change between Ishikawa-02 SC and Ishikawa-02 shSOX2

| PRJNA471843 | ENA

Infection of SC-beta cells with coxsackievirus B4 (CVB)

Project description:SC-beta cells were infected with CVB and collected over a time course.

2020-02-12 | GSE145074 | GEO

Ishikawa cell line LC-MS/MS analysis

Project description:The protein profile of Ishikawa cells, a widely used model for uterine lining cell studies, was examined. Additionally, we investigated potential disruptions caused by liposomes containing phosphatidylcholine and phosphatidylethanolamine, serving as models for drug delivery.

2024-08-17 | PXD050871 | Pride

ChIP sequencing following infection with CoV-02 Orf8 KO

Project description:ChIP sequencing performed on A549 cells following either Mock infection, infection with WT SARS-CoV-02, or infection with SARS-CoV-02 with Orf8 deletion

2022-07-21 | GSE186672 | GEO

Analysis of gene expression change between ectopic expression SOX2 in T24 bladder cancer cells.

Project description:We collected total RNA from both T24-Ctrl and T24-SOX2 and examined mRNA expression profile, comprehensively.

2020-02-25 | GSE145826 | GEO

ChIP sequencing following infection with CoV-02 Orf8 or ARKSAP KO

Project description:ChIP sequencing performed on A549 cells following either Mock infection, infection with WT SARS-CoV-02, or infection with SARS-CoV-02 with Orf8 or ARKSAP deletion

2022-07-21 | GSE205369 | GEO

SC-beta vs SC-EC +/- IFN-G

Project description:The goal of this study was to identify transcriptional changes in SC-beta and SC-endothelial cells pre and post IFN-gamma stimulation. Specifically, to characterize the differential expression of immune cell ligands in these cells with respect to a partial inflammatory stimulus.

2022-12-23 | GSE200021 | GEO

SC-beta vs SC-EC +/- IFN-G

Project description:SC-beta vs SC-EC +/- IFN-G

| PRJNA822636 | ENA

Effects of Estrogen and Tamoxifen on Ishikawa cells after 24h and 48h

Project description:Treatment with the breast cancer drug tamoxifen confers a risk of developing uterine tumors or other endometrial pathologies. Tamoxifen is a selective estrogen receptor modulator, which demonstrates tissue-specific activity although the mechanisms remain poorly understood. Both estradiol and tamoxifen act as estrogen agonists on the human uterus, and therefore have the potential to promote carcinogenicity. Estradiol and tamoxifen elicit cellular responses via the estrogen receptors (ER), which are involved in multiple signalling pathways. The effects at the molecular level are further influenced by the differential recruitment of co-factors and the presence of specific promoter motifs in target genes. In this study, ER positive (+) Ishikawa cells are used as a model to investigate the overall effect of treatment with either 17b-estradiol or 4-hydroxytamoxifen on the gene expression profiles. Ishikawa cells were serum-starved for 72 hours prior to treatment with 10-8M 17b-estradiol (E2) or 10-6M 4-hydroxytamoxifen (tam) for 24 or 48 hours. Cells were collected for total RNA extraction, and the quality and quantity of the RNA was determined spectrophotometrically. cDNA was prepared from treated (tam or E2) and control (vehicle only) Ishikawa cells, and was both forward and reverse labelled using Cy-3 dUTP/ Cy-5 dUTP and hybridised to oligo microarray slides representing >19,000 human genes (MRC HGMP-RFC). The data were analysed using GenePix Pro 3.0 software (Axon instruments) and statistical analyses applied to select significant gene changes (p<0.05).

2010-07-01 | E-GEOD-3762 | biostudies-arrayexpress

Next-generation Sequencing contributes to Quantitative Analysis of Transcriptomes in circBNC2-KO L-02 cells

Project description:Purpose: We idenficied a circRNA, circBNC2, that was downregulated during hepatocytes injury. To study the function of circBNC2, we performed CRISPR-Cas9 to knock out circBNC2 in L-02 (a well recognized human hepatocytes) cells. Next-generation Sequencing was used to identified the differentially expressed mRNA between circBNC2-KO L-02 cells and wild-type L-02 cells.

2022-07-01 | GSE179620 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data