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Gene expression regulated by warm temperature in C. elegans

ABSTRACT: Stress resistance induced by mild environmental stress protects animals against aging-associated cellular damages and promotes longevity. Here, we reveal that mild heat triggers innate immune and detoxification responses that confers longevity at warm temperatures. We compared the transcriptome of 25°C-cultivated animals to that of 15°C controls through RNA-seq analysis. A total of 1958 transcripts were differentially regulated, with 1143 up-regulations and 815 down-regulations.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE115095 | GEO | 2019/04/18

REPOSITORIES: GEO

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