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DNA-dependent protein kinase drives prostate cancer progression through transcriptional regulation of the Wnt signaling pathway

ABSTRACT: DNAPK was identified as the most significantly expressed kinase associated with metastatic progression in high-risk prostate cancer. GSEA analysis on DNAPK knockdwon samples and on patient data nominated Wnt signaling as the top pathway associated with DNAPK Our data indicates that DNAPK regulates Wnt signaling pathway.

ORGANISM(S): Homo sapiens

PROVIDER: GSE116895 | GEO | 2019/10/01

REPOSITORIES: GEO

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