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Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV

ABSTRACT: Using single cell RNA sequencing (scRNA-seq) on cerebrospinal fluid (CSF) and blood from adults with HIV, we identified a rare (<5% of cells) subset of myeloid cells that are found only in CSF and that present a gene expression signature that overlaps significantly with neurodegenerative disease associated microglia

ORGANISM(S): Homo sapiens

PROVIDER: GSE117397 | GEO | 2018/09/20

REPOSITORIES: GEO

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