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Identification of differentially expressed miRNAs in exosomes secreted from human colon cancer stem cells.

ABSTRACT: As accumulating evidence suggests cancer cells exhibit stem-like properties for advanced diseases and cancer stem cells (CSCs) have been identified in various tumor types, revisiting present knowledge toward CSCs is essential. The identification of exosome-loaded miRNAs responsible for stemness and chemoradioresistance of CSCs should eventually leadd to development of novel therapeutic approaches.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117479 | GEO | 2021/07/01

REPOSITORIES: GEO

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