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SNON and Arkadia (RNF111) regulate TGFβ-SMAD2/3 dose-dependent responses

ABSTRACT: The purpose of this RNA-seq experiment was to identify Activin A target genes that were differentially expressed in wild type and Arkadia null mouse embryonic stem cells (ESC). We performed the RNA sequencing experiment in two different wt and Arkadia-/- ESC under conditions of signalling inhibition SB431542 (SB; T0) and signalling stimulation with Activin A for 3 and 6 hours (T3 and T6 respectively).

ORGANISM(S): Mus musculus

PROVIDER: GSE118005 | GEO | 2018/08/02

REPOSITORIES: GEO

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Analysis of chromatin accessibility upon NODAL/Activin signalling reveal mechanisms of SMAD2-regulated transcription

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