Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Maternal Nematode Infection Up-regulates Expression of Genes Associated with Long-Term Potentiation in Brains of Uninfected Pups

ABSTRACT: Pregnant mice were infected with Heligmosomoides bakeri nematode on gestation day 7, 12 and 17 and on postnatal day 3. Pup brain were collected on postnatal day 2 and 7 and sequenced in illumina HiSeq4000 PE100 sequencing lane

ORGANISM(S): Mus musculus

PROVIDER: GSE118064 | GEO | 2019/04/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Extracellular vesicles from Heligmosomoides bakeri and Trichuris muris contain distinct small RNAs

Project description:We report the small RNA content of extracellular vesicles (EVs) from adult parasite Trichuris muris and Heligmosomoides bakeri

2020-08-01 | GSE152591 | GEO

Heligmosomoides bakeri

Project description:Heligmosomoides bakeri overview

| PRJNA902479 | ENA

The production of Excretory-Secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures.

Project description:In this study, the composition of ES of male and female L4 stage Heligmosomoides polygyrus bakeri in the presence (cultured together) or absence (cultured alone) of the opposite sex was examined using mass spectrometry.

2021-09-10 | PXD023759 | Pride

Placental gene expression in intestinal nematode-infected and protein-deficient mice

Project description:Protein deficiency and intestinal parasite infection during pregnancy impair fetal growth through passage of signals from the maternal environment which signal impairment of fetal growth. The placenta is an important regulator of the transfer of these signals through differential expression of key placental genes. We used microarrays to examine placental gene expression responses to maternal protein deficiency (6% vs. 24% protein) and Heligmosomoides bakeri infection. 2x2 factorial.

2015-09-09 | E-GEOD-57115 | biostudies-arrayexpress

nxHelBake2

Project description:Heligmosomoides bakeri genome assembly, nxHelBake2

| PRJEB67323 | ENA

Project description:scRNA-seq of Heligmosomoides bakeri

| PRJNA1009113 | ENA

nxHelBake1

Project description:Heligmosomoides bakeri genome assembly, nxHelBake1

| PRJEB57615 | ENA

nxHelBake3

Project description:Heligmosomoides bakeri genome assembly, nxHelBake3

| PRJEB67321 | ENA

Maternal IgG Affects Brain Development of Mouse Pups

Project description:Maternal IgG is an immunoglobulin present in breast milk and has been shown to play a role in the development of the immune system in infants. The aim of this study was to investigate the effects of maternal IgG on brain development in mouse pups. Maternal IgG immunoreactivity was observed in microglial cells of the pup brain, peaking at postnatal 8 day. In particular, strong IgG immunoreactivity was observed in the microglia in the corpus callosum and cerebellar white matter. IgG stimulation of primary cultured microglia resulted in activation of the type I interferon feedback loop by Syk. Among the IgG subclasses, IgG2a was found to have a strong influence on microglia. Analysis of FcRn KO mice that were unable to take up IgG from their mothers revealed that these mice had abnormalities in the proliferation and/or survival of microglia, oligodendrocytes, and some types of interneurons. FcRn KO mice also exhibited abnormalities in social behavior and adaptation to novel environments. This study suggests that maternal IgG affects brain development in pups.

2024-05-24 | GSE248310 | GEO

Project description:Nanopore RNA-seq of Heligmosomoides bakeri

| PRJNA1050269 | ENA