The genomic tandem quadruplication is associated with ketoconazole resistance of Malassezia pachydermatis
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ABSTRACT: Purpose: Understanding the ketoconazole resistance mechanism in Malassezia pachydermatis Methods: The transcriptome profile of the ketoconazole resistant M. pachydermatis KCTC 27587 cells compared to that of ketoconazole sensitive M. pachydermatis CBS 1879 cells were generated by RNA-Seq using Illumina HiSeq. Results: The expressions of genes in the region of quadruplicated chromosome 4 were up-regulated.
ORGANISM(S): Malassezia pachydermatis
PROVIDER: GSE118354 | GEO | 2019/02/07
REPOSITORIES: GEO
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