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Gene expression changes in PC12 cells expressing GFP-mHtt-74Q treated with Guanabenz analogues

ABSTRACT: To gain an overview of the cellular impact of Guanabenz analogues, we analyzed the gene expression changes in PC12 cells expressing GFP-mHtt-74Q utilizing Affimatrix rat genome microarrays. Following exposure of PC12 cells expressing GFP-mHtt-74Q to Compound 6 for 48 hrs, we noted the enhanced expression of over 46 genes and the reduced expression of 8 genes compared to DMSO

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE119557 | GEO | 2019/09/05

REPOSITORIES: GEO

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