Transcriptomics

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Atopic Dermatitis, Psoriasis and healthy control RNA-seq cohort


ABSTRACT: To gain a deeper understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic study of AD with deeply-sequenced RNA-seq samples using long (125b) paired-end reads. By integrating deep sequencing-based skin transcriptome profiling with systems biology analysis, we are able to provide deep characterization for the expression signatures for AD, and by including psoriasis samples in the analysis, we can reveal the distinct molecular features of uninvolved and lesional skin of AD that have not been previously described.

ORGANISM(S): Homo sapiens

PROVIDER: GSE121212 | GEO | 2019/01/18

REPOSITORIES: GEO

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