Gut microbiome communication with the bone marrow regulates intestinal inflammation and susceptibility to amebiasis.
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ABSTRACT: We discovered that colonization of the gut with the human bile acid 7'-dehydroxylating bacteria Clostridia scindens provided immunity to the parasite E. histolytica in a murine model, increased granulocyte monocyte progenitors, and that adoptive marrow transplant from C. scindens colonized mice into naive mice could recapitualte this protection.
ORGANISM(S): Mus musculus
PROVIDER: GSE121503 | GEO | 2020/08/10
REPOSITORIES: GEO
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