Genomics

Dataset Information

0

A distinct motif for numerous CTCF binding sites in the murine IgH locus


ABSTRACT: Our studies have revealed that a large class of CTCF binding sites – namely the upstream sites – conform neither to a conformational nor a local recombinase activating role. Their conserved spatial distances upstream of V gene segments suggests a possible role in insulating V gene segments from neighboring V gene segments. In any case, understanding the sequence determinants of CTCF binding to the murine IgH locus should facilitate future studies evaluating how IgH locus accessibility regulates CTCF binding as well as the functions that CTCF plays in regulating the recombinational accessibility of VH gene segments during B cell development.

ORGANISM(S): Mus musculus

PROVIDER: GSE124153 | GEO | 2019/07/02

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2013-08-05 | E-GEOD-47766 | biostudies-arrayexpress
2024-04-08 | GSE263123 | GEO
2024-04-08 | GSE254039 | GEO
2013-08-05 | E-GEOD-47885 | biostudies-arrayexpress
| PRJNA510845 | ENA
2013-08-05 | GSE47766 | GEO
2013-08-05 | GSE47885 | GEO
2020-05-11 | GSE142779 | GEO
2020-05-11 | GSE142778 | GEO
2020-05-11 | GSE142777 | GEO