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Manganese detoxification by Staphylococcus aureus

ABSTRACT: Manganese (Mn) is an essential micronutrient critical for the pathogenesis of Staphylococcus aureus, a significant cause of human morbidity and mortality. Paradoxically, excess Mn is toxic, therefore maintaining intracellular Mn homeostasis is required for survival. To identify gene candidates that contribute to manganese detoxification, we compared the transcriptional response of S. aureus cells exposed to 1 mM MnCl2 and those that were untreated.

ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman

PROVIDER: GSE124285 | GEO | 2019/01/01

REPOSITORIES: GEO

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Manganese detoxification by Staphylococcus aureus

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