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Hypothalamus of diet-induced obese (DIO) mice treated with celastrol or DMSO

ABSTRACT: Since leptin signaling in the hypothalamus is critical to regulate food intake and body weight, we investigated how celastrol alters the hypothalamic transcriptome of DIO mice. By doing this analysis, genes with potential relevance for celastrol-mediated leptin sensitization could be identified.

ORGANISM(S): Mus musculus

PROVIDER: GSE124353 | GEO | 2018/12/27

REPOSITORIES: GEO

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The protective effect of celastrol in ANIT-induced cholestasis

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