Transcriptomics

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Inducible bronchus-associated lymphoid tissues (iBALT) serve as sites of B cell selection and maturation following influenza infection in mice


ABSTRACT: GC-like structures within iBALT serve as a distinct niche that independently support the maturation and selection of B cells primarily targeted against the influenza virus nucleoprotein. Our findings suggest that iBALT, which are positioned at the frontline of the lung mucosa, drive long-lived and unique GC reactions that contribute to the diversity of the humoral response targeting influenza.

ORGANISM(S): Mus musculus

PROVIDER: GSE124369 | GEO | 2019/03/14

REPOSITORIES: GEO

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