A wave of Foxp3 + regulatory T cell accumulation in the neonatal liver plays unique roles in maintaining self-tolerance

ABSTRACT: The liver in newborn animals undergo a maturation process in order to adapt to a plethora of changes and challenges in the extra-uterine life. The influx of regulatory T cells during 1-2-week period protect the animals from autoimmune hepatitis and govern the transformation of a neonatal liver to a crucial metabolic organ in adults.

ORGANISM(S): Mus musculus

PROVIDER: GSE124536 | GEO | 2022/01/02

REPOSITORIES: GEO