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RNA sequencing of murine C2C12 cell treated with high-throughput screening hit compound 6,8-dimethyl-3-(4-phenyl-1H-imidazol-5-yl)quinolin-2(1H)-one.

ABSTRACT: The hit compound promotes expression and acitivity of alkaline phosphatase in murine cells that are bipotential for myogenic and osteoblastogenic differentiaion. RNA sequecing was performed to assess global transcript expression, with particular attention to genes indicative of osteoblast and bone differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE125052 | GEO | 2020/01/15

REPOSITORIES: GEO

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