Transcriptomics

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RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown


ABSTRACT: Genome-wide association studies of tumor samples have identified a large number of lncRNAs associated with various types of cancer including colorectal cancer. To elucidate the mechanism by which CASC9 regulates colorectal cancer cell growth, RNA-sequencing was performed to analyze the gene expression profile affected by CASC9 knockdown. A total of 249 significantly upregulated genes and 491 significantly downregulated genes (absolute fold change ≥ 2, P < 0.05) were found in CASC9 knockdown HCT-116 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125648 | GEO | 2019/06/24

REPOSITORIES: GEO

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