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IPS derived microglia like cells cultured with human neurons and astrocytes

ABSTRACT: In this article, Jose Polo and colleagues molecularly compare existing microglia differentiation methods from stem cells, generate a new dual fluorescent and enzymatic reporter tool to study microglia in vitro and in vivo and show that human astrocyte/neuron co-culture pushes the regulatory landscape of in vitro microglia-like cells to more closely resemble bona fide microglia.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125872 | GEO | 2020/05/22

REPOSITORIES: GEO

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