RNA Sequencing Analysis of macrophage and CD4+T cells from Wild Type and Gsdmd-/- mice
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ABSTRACT: We identified that GSDMD was required for the pathogenesis of EAE, and GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS , leading to the suppression of neuroinflammation and demyelination.The purpose of this experiment was to identify how GSDMD induces EAE.
ORGANISM(S): Mus musculus
PROVIDER: GSE126289 | GEO | 2019/08/22
REPOSITORIES: GEO
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