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Effect of Rgnef knockout in an aggressive ovarian cancer cell line

ABSTRACT: CRISPR/Cas9-mediated Rgnef knockout was performed in the aggressive ID8-IPs (alternaate name is KMF cells). Gene expression profiles of Rgnef-/- or Rgnef-/- cells re-expressing GFP-Rgnef were generated. Differential downregulation of antioxidant genes was observed in Rgnef-/- cells. Results provide insight into the role of Rgnef in promoting ovarian tumor progression.

ORGANISM(S): Mus musculus

PROVIDER: GSE126560 | GEO | 2019/07/01

REPOSITORIES: GEO

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