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Whsc1 controls mesendodermal transcription factor expression

ABSTRACT: We report here chromatin related factor Whsc1 links pluripotency exit and mesendodermal differentiation. We performed RNA-seqs to compare Whsc1+/+ and Whsc1-/- embryonic stem cells (ESCs) to compare the transcriptomes. UMI-4C experiments have been performed to identify regions having contacts with promoter regions of downstream Whsc1 targets: the mesendoderm transcritpion factors

ORGANISM(S): Mus musculus

PROVIDER: GSE126618 | GEO | 2019/06/20

REPOSITORIES: GEO

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Whsc1 controls mesendodermal transcription factor expression

Project description:Whsc1 controls mesendodermal transcription factor expression

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