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GEF-H1-IRF5 mediated gene expression changes in BMDM by MDP recognition

ABSTRACT: The transcription factor IRF5 is essential for immune defense against pathogens. Here, the authors show that the microtubule-associated factor GEF-H1 plays a critical role in host defense against Listeria monocytogenes in macrophages via activation of the IRF5 kinase IKKe

ORGANISM(S): Mus musculus

PROVIDER: GSE126749 | GEO | 2019/04/02

REPOSITORIES: GEO

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GEF-H1-IRF5 mediated gene expression changes in BMDM by MDP recognition

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