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Transcriptional analysis of skeletal muscles from wild type and mdx/mTR mice

ABSTRACT: We report RNA sequencing data from tibialis anterior muscles of 4 month old male wild type C57Bl/6 mice and mdx/mTR mice (generated in the C57Bl/6 background), which lack the dystrophin and telomerase RNA component genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE127929 | GEO | 2019/03/06

REPOSITORIES: GEO

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iTRAQ Protemics of mdx vs. mdx/Actg1-TG mouse skeletal muscle

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Project description:There are two groups of mice in the study, wild type mice (WT) and mdx/mTR mice (mdx or mdx/mTR) that are a model of musclar dystrophy. We collected the tibialis anterior muscles from these mice (N=6 in each group), and would like to perform TCA-plus analysis and shotgun lipidomics analysis on the mice, and compare across the two groups.

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Transcriptional analysis of skeletal muscles from wild type and mdx/mTR mice

Project description:Transcriptional analysis of skeletal muscles from wild type and mdx/mTR mice

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Transcription profiling of 16-week-old mdx mouse muscles to characterize transcriptional changes induced by dystrophin deficiency.

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