Transcriptomics

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Real-time quantitative PCR analysis of mouse colon samples


ABSTRACT: Gut mucosal healing (MH) is considered a key therapeutic target and prognostic parameter in the management of inflammatory bowel disease (IBD). The dipotassium glycyrrhizate (DPG), a salt of the glycoconjugated triterpene glycyrrhizin, has been shown to inhibit the High Mobility Group Box 1 (HMGB1) protein, an allarmin strongly implicated in the pathogenesis of most inflammatory and auto-immune disorders, included IBD. The aims of the present study is to identify genes involved in MH pathways modulated by DPG in mouse model of chemical induced acute colitis.

ORGANISM(S): Mus musculus

PROVIDER: GSE127953 | GEO | 2019/03/07

REPOSITORIES: GEO

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