Full-length transcriptome reconstruction reveals large diversity of RNA isoforms and open reading frames in rat hippocampus
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ABSTRACT: We developed a hybrid-sequencing workflow, combining next-generation and third-generation sequencing, to reconstruct full-length transcriptomes. Integrating with polysome profiling and ribosome footprinting data, we predicted isoform–specific translational status and reconstructed ORFeome. Moreover, we identified isoforms with specific subcellular localization pattern in neurons.
ORGANISM(S): Rattus norvegicus
PROVIDER: GSE128136 | GEO | 2019/10/14
REPOSITORIES: GEO
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