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Landscape profiling of small RNAs in extracellular vesicles secreted by senescent human stromal cells after DNA damage treatment

ABSTRACT: Blooming advancements in next generation sequencing (NGS) have revolutionized system-based analysis of genome-wide expression, cellular pathways and stress responses. We performed this non-coding RNA-associated milestone study to document comprehensively the small RNA molecules carried by extracellular vesicles (EVs) from human stromal cells, which develop typical cellular senescence and manifest the senescence-associated secretory phenotype (SASP) after genotoxic stress in culture.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128927 | GEO | 2022/12/31

REPOSITORIES: GEO

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