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Effect of rosiglitazone treatment on insulin sensitivity in adipose tissue of type 2 diabetic patients

ABSTRACT: The goal of this study was to analyse the effect of a 12 weeks treatment with rosiglitazone on insulin sensitivity in the adipose tissue of type 2 diabetic patients. Diabetic patients were submitted to a 3 hours hyperinsulinemic- euglycemic clamp. Adipose tissue biopsies were taken before and after the clamp, labelled A & B respectively. Then, the patients were treated with rosiglitazone, agonist of PPAR gamma, during 12 weeks. After the treatment, all the patients were submitted to a second 3 hours hyperinsulinemic-euglycemic clamp. Adipose tissue biopsies were taken before and after the clamp, labelled C & D respectively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE12894 | GEO | 2018/04/20

REPOSITORIES: GEO

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| PRJNA105677 | ENA

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