Identification of renal resident macrophages across species [10X]
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ABSTRACT: We use single cell RNA sequencing to identify an evolutionarily conserved gene expression signature in resident macrophages. Based on our single cell data, we show the presence of a core gene expression signature in a cluster of innate immune cells in mouse, rat, pig, and human kidney tissue. Further, using this gene expression signature, we identify novel candidate markers for resident macrophages that span all 4 species tested.
ORGANISM(S): Mus musculus Rattus norvegicus Homo sapiens Sus scrofa
PROVIDER: GSE128992 | GEO | 2019/04/05
REPOSITORIES: GEO
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