Genomics

Dataset Information

0

Genome-wide maps of histone crotonylation in pluripotent and endoderm cells. [ChIP-Seq]


ABSTRACT: We examined the genome-wide distribution of histone crotonylation and H3K27ac in human embryonic stem cells and induced endoderm cells, by obtaining over four billion bases of sequence from chromatin immunoprecipitated DNA. When compared to H3K27ac, histone crotonylation was more enriched in metabolic genes and in promoters at pluripotent state, while H3k27ac was enriched in the enhancers of endoderm genes. After endoderm differentiation, histone crotonylation and H3K27ac were both enriched in endoderm genes. Moreover, the enrichment of histone crotonylation was more remarkable than that of H3K27ac. Our data indicate that histone crotonylation correlates with endoderm differentiation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE130344 | GEO | 2021/02/23

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2021-02-23 | GSE130341 | GEO
| PRJNA535524 | ENA
| PRJNA535529 | ENA
| PRJNA535602 | ENA
2011-10-06 | E-GEOD-32663 | biostudies-arrayexpress
2022-10-12 | PXD023270 | Pride
2024-06-18 | GSE241194 | GEO
2024-06-18 | GSE241193 | GEO
2022-10-03 | GSE214619 | GEO
2016-06-11 | MSV000079810 | MassIVE