Genome-wide miRNA analysis reveals different miRNAs between Tuberculous and viral Meningitis
Ontology highlight
ABSTRACT: In order to identify the potential biomarkers for discriminating tuberculous meningitis (TBM) and viral meningitis (VM) and to reveal the different pathophysiological processes between TBM and VM, a genome-wide miRNA screenings of peripheral blood mononuclear cells (PBMCs) from TBM, VM, and healthy controls (HCs) using microarray assay was performed (12 samples). Twenty-eight differentially expressed miRNAs were identified between TBM and VM, and 11 differentially expressed miRNAs were identified between TBM and HCs. The 6 overlapping miRNAs detected in both TBM vs. VM and TBM vs. HCs were verified by qPCR analysis and showed a 100% consistent result with that in microarray test.
ORGANISM(S): Homo sapiens
PROVIDER: GSE131708 | GEO | 2019/10/02
REPOSITORIES: GEO
ACCESS DATA