Transcriptomics

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Global gene expression in mouse thymic tissue or lymphocytes from young or aged mice, and during induced regeneration


ABSTRACT: The thymus begins to atrophy early in life, but maintains the capacity for transient robust re-growth in response to chemical or physical androgen ablation in males. In mice, at age 5 weeks the thymus remains near peak size, while by 12 months it has atrophied by . In response to castration the thymus re-grows to approximately it's peak size after about 20 days when it begins to rapidly re-atrophy. This study contains gene expression data from affymetrix microarrays covering thymic cortical and medullary laser capture microdissected tissue as well as FACS sorted cortical and medullary lymphocytes in young and aged mice, as well as timecourse data during castration induced regrowth.

ORGANISM(S): Mus musculus

PROVIDER: GSE132136 | GEO | 2019/06/04

REPOSITORIES: GEO

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