Transcriptomics

Dataset Information

0

Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq]


ABSTRACT: We show that most binding events of NR2F2 occur together with the ERα binding sites.To address the functional relationship between NR2F2 and ERα, we assessed the role of NR2F2 in oestrogen-induced growth in ER positive cell line MCF-7. The MTT experiment showed that inhibition of NR2F2 prevented the oestrogen-induced proliferation of MCF-7 cells.To further explore the effect of NR2F2 on estrogen response, We expanded our knockdown studies by performing RNA-seq analysis for MCF-7 cells transfected with control or NR2F2 shRNAs with or without E2.

ORGANISM(S): Homo sapiens

PROVIDER: GSE132433 | GEO | 2019/10/15

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-10-15 | GSE132432 | GEO
2019-10-15 | GSE132434 | GEO
| PRJNA548079 | ENA
2014-06-21 | GSE57935 | GEO
2023-02-12 | GSE102552 | GEO
2013-05-29 | E-GEOD-47438 | biostudies-arrayexpress
2023-02-12 | GSE102553 | GEO
| PRJNA548082 | ENA
2020-12-15 | E-MTAB-9599 | biostudies-arrayexpress
2008-10-25 | E-GEOD-12846 | biostudies-arrayexpress