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Canine CNVs associated with canFam2 segmental duplications

ABSTRACT: This study centered on using a custom made Nimblegen aCGH chip that targeted all segmental duplications in the canine genome to identify associated CNVs. A total of 19 hybridizations were performed in a panel of diverse dogs and a single wolf.

ORGANISM(S): Canis lupus familiaris Canis lupus

PROVIDER: GSE13266 | GEO | 2008/10/31

SECONDARY ACCESSION(S): PRJNA109559

REPOSITORIES: GEO

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Canine CNVs associated with canFam2 segmental duplications

Project description:This study centered on using a custom made Nimblegen aCGH chip that targeted all segmental duplications in the canine genome to identify associated CNVs. A total of 19 hybridizations were performed in a panel of diverse dogs and a single wolf. Using computational approaches all segmental duplications were identified in the canFam2 genome of the dog. A custom aCGH chip was then built that densely interrogated these segmental duplications for CNVs in a panel of diverse dog breeds and a single wolf.

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