Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome-wide gene-expression analysis of colonic epithelium from enteroendocrine cell-deficient mice

ABSTRACT: The goal of this study is to study the consequence of EEC loss on the colonic epithelium through tissue specific deletion of the transcription factor Ngn3.

ORGANISM(S): Mus musculus

PROVIDER: GSE134202 | GEO | 2019/07/13

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

ChIP-seq of Colonic Intestine Epithelium from Satb2-deficient and WT mice

Project description:We use ChIP-seq to understand the genomic binding sites of SATB2 in colonic epithelium and to study the shifting of CDX2 and HNF4A's genomic binding sites after SATB2 loss in colonic epithelium.

2021-10-05 | GSE167287 | GEO

Bulk RNA-seq (>20M reads) of colonic epithelium from Vil-CreER;MTA2F/F (MTA2KO) and Wild Type mice

Project description:RNA-sequening colonic epithelium with deeper reads to evaluate consequence of mta2 gene loss in the colonic epithelium.

2024-03-07 | GSE213879 | GEO

Transcriptome-wide gene-expression analysis of colonic epithelium from enteroendocrine cell-deficient mice

Project description:Transcriptome-wide gene-expression analysis of colonic epithelium from enteroendocrine cell-deficient mice

| PRJNA554303 | ENA

Bulk RNA-seq (>20M reads) of Intestine Epithelium (Ileum and Colon) from Satb2-deficient and WT mice

Project description:Resequening ileum and colon epithelium with deeper reads to evaluate consequence of Satb2 gene loss in the colonic epithelium. The same library construction method was used to compare with Bulk RNA-seq data from In Vitro cultured mouse organoids.

2021-10-05 | GSE167284 | GEO

Colonic epithelium of WKY and SHR

Project description:Colonic epithelium of WKY and SHR

| PRJNA540986 | ENA

Bulk RNA-seq of Intestine Epithelia (Jejunum, Ileum, Cecum and Colon) from Satb2-deficient and WT mice

Project description:The goal of this study is to study the consequence of Satb2 gene loss in the colonic epithelium.

2021-10-05 | GSE148692 | GEO

Expression data from heterotopically grafted mouse small intestinal epithelium and the normal colonic epithelium

Project description:Epithelia of small and large intestines differ in their structures and functions. Such heterogeneity between these two epithelial tissues might be controlled by both epithelium-intrinsic and -extrinsic programs. By employing the cell transplantation technique developed in our laboratory, we investigated how adult SI epithelial cells behave when heterotopically transplanted onto colon. Then the gene expression profiles of small intestinal epithelium heterotopically transplanted onto colon and control colonic epithelium were compared. We used laser capture microdissection and microarray analysis to compare the global gene expression profiles of small intestinal epithelium in the heterotopically grafted tissues and control colonic epithelium.

2014-08-15 | GSE59410 | GEO

Expression data from heterotopically grafted mouse small intestinal epithelium and the normal colonic epithelium

2014-08-15 | E-GEOD-59410 | biostudies-arrayexpress

ChIP-seq of colonic intestine epithelium from Vil-CreER;MTA2F/F (MTA2KO), Vil-CreER;SATB2F/F(SATB2KO) and Wild Type mice

Project description:We use ChIP-seq to understand the genomic binding sites of MTA2 in colonic epithelium and to study the shifting of SATB2 and HNF4A's genomic binding sites after MTA2 loss in colonic epithelium.

2024-03-08 | GSE213877 | GEO

Transcription profiling by array of Apc-deficient proximal colonic epithelium upon Msx1 transcription factor depletion

Project description:The first step in the development of human colorectal cancer (CRC) is the aberrant hyperactivation of the Wnt signaling pathway, predominantly caused by inactivating mutations in the adenomatous polyposis coli (APC) gene which encodes an essential tumor suppressor. In order to identify genes affected by Apc loss, expression profiling of intestinal epithelium isolated from mice harboring the conditional allele of the gene was performed. The gene encoding transcriptional factor msh homeobox 1 (Msx1) displayed robust upregulation upon Apc inactivation. To characterize the gene signature in colon upon Msx1 depletion, colonic epithelium from mice harboring conditional alleles of Apc and Msx1 was isolated and the gene expression profile was compared with control mice harboring the conditional allele of Apc only.

2019-11-01 | E-MTAB-6909 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data