Genomics

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Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection [ChIP-seq]


ABSTRACT: Using ChIP-seq we show that total H3Ac within ± 10,000 bp of all genomic transcription start sites was decreased by approximately two-fold in MDSCs recovered from mice infected with a triple mutant, unable to make lactate, compared to WT S. aureus.

ORGANISM(S): Mus musculus

PROVIDER: GSE135494 | GEO | 2020/06/17

REPOSITORIES: GEO

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