Transcriptomics

Dataset Information

0

Fosl1 regulates mesenchymal GBM plasticity


ABSTRACT: Despite recent advances in genomic profiling techniques, the precise mechanisms controlling GBM subtypes and their plasticity are not fully unraveled. Here,using transcriptomic data of patient derived stem cell lines we found that FOSL1 is a master regulator of the MES subtype. Depletion of FOSL1 resulted in loss of themesenchymal gene signature (MGS) in mouse Kras-mutant neural stem cells and in human brain tumor stem cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE138010 | GEO | 2020/09/30

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA574145 | ENA
2023-08-10 | GSE196596 | GEO
2017-06-12 | GSE76290 | GEO
2016-12-23 | E-MTAB-4299 | biostudies-arrayexpress
2015-06-30 | E-GEOD-68272 | biostudies-arrayexpress
2021-04-14 | GSE151132 | GEO
2024-08-01 | GSE273252 | GEO
2024-08-01 | GSE273250 | GEO
2021-12-22 | GSE192406 | GEO
2021-11-02 | PXD025729 | Pride