Genomics

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ChIP-seq analysis of MED1 and FOSL1 in SCC1 cells after depletion of FOSL1


ABSTRACT: To explore genome-wide alteration MED1 and FOSL1 after depletion of FOSL1, we performed chromatin immunoprecipitation sequencing (ChIP-seq) of SCC1 cells to examine genome-wide recruitment of MED1 and FOSL1 following FOSL1 knockdown. Depletion of FOSL1 led to dramatically loss of the recruitment of MED1 and FOSL1 at a cohort of key oncogenes associate with tumorigenesis and metastasis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE151132 | GEO | 2021/04/14

REPOSITORIES: GEO

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