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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq]

ABSTRACT: iPSC derived microglial precursors were tranplanted into the brains of neonatal mice, FACS sorted out based on GFP+ following 2 months, and compared to in vitro differentiated iPSC derived microglia from the same precursors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE139193 | GEO | 2019/11/27

REPOSITORIES: GEO

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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Bulk RNAseq]

Project description:iPSC derived microglial precursors were transplanted into the brains of neonatal mice, FACS sorted out based on GFP+ following 2 months, and compared to in vitro differentiated iPSC derived microglia from the same precursors.

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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain

Project description:Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain

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Location of Neonatal Microglia Drives Small Extracellular Vesicles Content and Biological Functions

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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Bulk RNAseq]

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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq]

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