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Microarray analysis of the synovial membrane of rheumatoid arthritis patients undergoing anti-TNF therapy

ABSTRACT: Synovial biopsies of Rheumatoid Arthritis patients were obtained at week 20 of anti-TNF therapy. The clinical response to therapy was determined comparing the DAS28 at this time point with the baseline DAS28, using the EULAR response criteria. Gene expression profiles of patients responding to anti-TNF therapy were compared to non-responders and different genes, pathways and deconvoluted cell types were found to be differential between both groups of rheumatoid arthritis patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE140036 | GEO | 2020/06/30

REPOSITORIES: GEO

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