Transcriptomics

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Transcriptomic analysis of SRSF1 overexpression and imatinib treatment in K562 CML cell lines


ABSTRACT: Using RNA-sequencing, we report the effects of overexpressing the proto-oncogene SRSF1 in K562 cells on gene expression and alternative splicing. We found that overexpressing SRSF1 antagonized the gene expression changes brought about by imatinib treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE140322 | GEO | 2020/07/08

REPOSITORIES: GEO

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