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Efficacy and safety of ustekinumab treatment in adults with moderate-to-severe atopic dermatitis

ABSTRACT: This was a phase II, randomized, placebo-controlled, double-blinded single center study (clinicaltrials.gov: NCT01806662) to investigate safety and efficacy of ustekinumab treatment in moderate-to-severe AD patients. Patients underwent 1:1 randomization using a computer generated subject randomization table by an unblinded pharmacist. to Subjects received subcutaneous ustekinumab or placebo at weeks 0, 4, and 16 with a crossover to the other agent (either ustekinumab or placebo) at weeks 16, 20, and 32 (Figure 1A) to ensure patient retention.

ORGANISM(S): Homo sapiens

PROVIDER: GSE140684 | GEO | 2019/11/20

REPOSITORIES: GEO

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