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The role of histone H3K27 acetylation for enhancer activity in embryonic stem cells

ABSTRACT: By substituting lysine 27 in histone variant H3.3 to arginine in mouse embryonic stem cells, we measured H3K27ac/H3K4me1/H3K4me3 and other acetylation modifications in H3.3K27R mutant cells, together with RNA-seq and ATAC-seq to measure the transcription activity and chromatin accessibility, respectively.

ORGANISM(S): Mus musculus

PROVIDER: GSE141525 | GEO | 2020/02/09

REPOSITORIES: GEO

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