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Gene expression changes in IDH mutant or IDH wildtype gliomas treated with All-trans Retinoic Acid

ABSTRACT: IDH mutant cells are deficient in retinoic acid production, which impacts downstream gene expression and pathways. We looked at the effect of supplementing IDH mutant glioma cells with ATRA on gene expression and downstream pathways. We compared gene expression changes with IDH WT cells that were also treated with ATRA

ORGANISM(S): Homo sapiens

PROVIDER: GSE141789 | GEO | 2019/12/11

REPOSITORIES: GEO

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